Crocin CAS#42553-65-1
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Excellent Water Solubility: Easily soluble in hot water, producing a clear and bright orange-yellow solution suitable for aqueous formulations.
Good Light and Heat Stability: Demonstrates favorable resistance to light and heat under neutral or alkaline conditions.
Wide pH Stability Range: Its coloring performance remains relatively stable across a broad pH range of approximately 4–10.
Strong Coloring Performance: Provides effective coloring properties, particularly for protein-based materials, with better performance than for starch and good resistance to most metal ions.
Crocin CAS#42553-65-1
Crocin is a reddish-brown, needle-like crystalline compound with a slight odor. It is readily soluble in hot water, forming an orange-colored solution, and is slightly soluble in anhydrous ethanol, ether, and other organic solvents. It is insoluble in oils.
Its aqueous solution is weakly acidic to neutral and exhibits a transparent, bright yellow color with a maximum absorption wavelength of 442 nm. The color is largely unaffected by changes in pH. Crocin demonstrates good resistance to light and heat under neutral or alkaline conditions, although its stability is relatively poor in acidic environments.
It also shows good resistance to most metal ions, except iron, which may cause darkening. Crocin provides better coloring performance in proteins than in starch and maintains its coloring ability across a pH range of 4–10.
Crocin Chemical Properties
| Melting point | 186° (effervescence) |
| Boiling point | 1169.0±65.0 °C(Predicted) |
| density | 1.54±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly, Heated), Methanol (Very Slightly, Sonicated) |
| pka | 12.20±0.70(Predicted) |
| form | Powder |
| color | Orange to Very Dark Purple |
| Merck | 142589 |
| Stability: | Light Sensitive |
| Major Application | diagnostic assay manufacturing |
| hematology | |
| histology | |
| Cosmetics Ingredients Functions | ANTIOXIDANT |
| COLORANT | |
| InChIKey | OXNHRKGZZFWUQZ-QORFUXSJSA-N |
| LogP | -4.742 (est) |
| CAS DataBase Reference | 42553-65-1 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | HL7380000 |
| F | 37113 |
| HS Code | 32129000 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 42553-65-1(Hazardous Substances Data) |
Product Application of Crocin CAS#42553-65-1
Crocin is a natural carotenoid primarily derived from the flowers of crocus and gardenia plants. It is known for its potent antioxidant properties and has demonstrated antiproliferative activity against cancer cells in vitro. In addition, crocin has shown potential antidepressant properties, supporting its broad research and application potential.



