Palmitoyl Tripeptide-1 CAS#147732-56-7

  • Effective Signal Peptide Activity: Functions as a signal peptide that communicates with skin cells and stimulates collagen synthesis, helping improve skin firmness and elasticity.

  • Enhanced Skin Penetration Ability: The attachment of palmitic acid improves its skin permeability and oil solubility, enhancing its performance in cosmetic formulations.

  • Small Molecular Structure for Efficient Action: Composed of a three-amino-acid sequence (glycine-histidine-lysine, GHK), allowing targeted interaction with skin cells.

  • Anti-Aging Cosmetic Potential: Supports skin rejuvenation applications by promoting collagen-related processes, making it valuable for anti-aging skincare products.


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Products Description of Palmitoyl Tripeptide-1 CAS#147732-56-7

Peptides are compounds formed by linking two or more amino acids and serve as the fundamental building blocks of proteins. They are generally classified into three major types: signal peptides, carrier peptides, and peptides that inhibit nerve signals.

As a signal peptide, Palmitoyl Tripeptide-1 functions as a cellular messenger, stimulating collagen synthesis and helping improve skin firmness. It is a small three-amino-acid peptide with the sequence glycine-histidine-lysine (GHK). By binding GHK with palmitic acid, a fatty acid, Palmitoyl Tripeptide-1 achieves enhanced skin penetration and improved oil solubility.

Palmitoyl Tripeptide-1 CAS#147732-56-7

Palmitoyl Tripeptide-1 Chemical Properties

Boiling point 913.0±65.0 °C(Predicted)
density 1.105
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 30 mg/ml
pka3.16±0.10(Predicted)
form A solid
color White to off-white
SequencePal-Gly-His-Lys
Cosmetics Ingredients FunctionsSKIN CONDITIONING
Cosmetic Ingredient Review (CIR)Palmitoyl Tripeptide-1 (147732-56-7)
InChIKeyBYUQATUKPXLFLZ-UIOOFZCWSA-N
SMILESC(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)CCCCCCCCCCCCCCC

Palmitoyl Tripeptide-1 CAS#147732-56-7

Product Application of Palmitoyl Tripeptide-1 CAS#147732-56-7

Palmitoyl Tripeptide-1 (Pal-GHK, SpecPed® PT1P) is widely used in anti-aging formulations and wrinkle care products, including gels, serums, lotions, and creams. As a signaling peptide involved in skin restructuring and repair processes, it works synergistically to help restore and maintain a youthful skin appearance.

Palmitoyl Tripeptide-1 CAS#147732-56-7

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