Sodium gluconate CAS#527-07-1
Excellent Chelating Performance: Effectively binds with various metal ions to form stable complexes, helping inhibit unwanted chemical reactions.
Environmentally Friendly and Biodegradable: Fully biodegradable and non-toxic, making it a sustainable alternative to conventional chelating agents such as EDTA.
Safe and Low Toxicity Profile: Demonstrates low acute toxicity toward aquatic organisms, supporting safer applications in environmentally conscious formulations.
Versatile Functional Applications: As the sodium salt of gluconic acid, it provides reliable performance and is widely suitable for cosmetic and chemical applications.
Sodium gluconate CAS#527-07-1
Sodium gluconate (CAS#527-07-1) is the sodium salt of gluconic acid. As a chelating agent, it binds stably with multiple ions, effectively inhibiting their participation in chemical reactions. Naturally occurring gluconates dissociate into gluconate anions and corresponding cations. This substance is fully biodegradable, non-toxic, and serves as an eco-friendly substitute for conventional chelators like EDTA in cosmetic applications. Furthermore, sodium gluconate exhibits low acute toxicity toward aquatic organisms.
Sodium gluconate Chemical Properties
Melting point | 170-175 °C |
alpha | [α]D20 +11~+13° (c=10, H2O) |
storage temp. | Store below +30°C. |
solubility | H2O: 0.1 g/mL, clear |
form | Crystalline Powder |
color | White to light beige |
Odor | wh. to ylsh. cryst. powd., pleasant odor |
PH | 7.0-8.0 (100g/l, H2O, 20℃) |
biological source | microbial |
Water Solubility | Very soluble in water; sparingly soluble in alcohol; insoluble in ether. |
Merck | 14,4456 |
BRN | 3919651 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Cosmetics Ingredients Functions | SKIN CONDITIONING |
InChI | InChI=1/C6H12O7.Na.H/c7-1-2(8)3(9)4(10)5(11)6(12)13;;/h2-5,7-11H,1H2,(H,12,13);;/t2-,3-,4+,5-;;/s3 |
InChIKey | MPPJUDJABRMYJR-QZHCVFHNNA-N |
SMILES | [C@@H](O)([C@@H](O)C(=O)O)[C@H](O)[C@H](O)CO.[NaH] |&1:0,2,7,9,r| |
LogP | -3.175 (est) |
CAS DataBase Reference | 527-07-1(CAS DataBase Reference) |
EPA Substance Registry System | Sodium gluconate (527-07-1) |
Safety Information
Safety Statements | 24/25 |
WGK Germany | 1 |
RTECS | LZ5235000 |
Autoignition Temperature | >200 °C |
TSCA | TSCA listed |
HS Code | 29181600 |
Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
Product Application of Sodium gluconate (CAS#527-07-1)
Sodium gluconate serves as a natural preservative, inhibiting microbial growth to ensure product safety for consumers. Additionally, it functions as a skin-conditioning agent and chelating agent, enhancing foam formation in cleansing products when used in hard water environments. This versatile ingredient is commonly incorporated into soap, sunscreen, shampoo, toothpaste, hair care products, makeup, and other personal care items.
Beyond personal care, sodium gluconate is utilized as a component in recording buffers for two-electrode voltage-clamp (TEVC) experiments in Xenopus laevis oocytes. It also acts as a sodium control in scientific applications.



