Dibenz[b,f]azepine-5-carbonyl chloride CAS#33948-22-0

Important Pharmaceutical Intermediate: Dibenz[b,f]azepine-5-carbonyl chloride is a valuable tricyclic heterocyclic intermediate widely used in pharmaceutical and fine chemical synthesis.
Reactive Carbonyl Chloride Functionality: The carbonyl chloride group provides high chemical reactivity, making it suitable for a variety of acylation and organic synthesis reactions.
Derived from Readily Available Precursor: It can be conveniently synthesized from 5H-dibenz[b,f]azepine, providing an efficient route for industrial and laboratory production.
Versatile Synthetic Applications: Its unique tricyclic structure makes it a useful building block for the preparation of complex heterocyclic compounds and pharmaceutical intermediates.

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Product Details

Dibenz[b,f]azepine-5-carbonyl Chloride CAS#33948-22-0

Dibenz[b,f]azepine-5-carbonyl chloride, also known as 5H-dibenz[b,f]azepine-5-carbonyl chloride, is a tricyclic heterocyclic compound. It can be prepared by the synthesis of 5H-dibenz[b,f]azepine and is widely used as an important intermediate in organic and pharmaceutical synthesis.

Dibenz[b,f]azepine-5-carbonyl chloride CAS#33948-22-0

Dibenz[b,f]azepine-5-carbonyl chloride Chemical Properties

Melting point	149-153 °C (lit.)
Boiling point	413.7±38.0 °C(Predicted)
density	1.316±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	soluble in Chloroform, Dichloromethane, Ethyl Acetate
form	Oil
pka	-3.69±0.20(Predicted)
color	Brown
InChI	InChI=1S/C15H10ClNO/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H
InChIKey	APJYHXJGXDPGBA-UHFFFAOYSA-N
SMILES	C(Cl)(N1C2=CC=CC=C2C=CC2=CC=CC=C12)=O
CAS DataBase Reference	33948-22-0(CAS DataBase Reference)
Hazard Codes	C
Risk Statements	34
Safety Statements	26-36/37/39-45
RIDADR	UN 3261 8/PG 2
WGK Germany	3
Storage Class	8A - Combustible corrosive hazardous materials
Hazard Classifications	Skin Corr. 1B

Dibenz[b,f]azepine-5-carbonyl chloride CAS#33948-22-0

Product Application of Dibenz[b,f]azepine-5-carbonyl Chloride CAS#33948-22-0

Dibenz[b,f]azepine-5-carbonyl chloride is used as an important intermediate in organic and pharmaceutical synthesis. It can be employed in the preparation of trans-10,11-dibromo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carbonyl chloride through bromination with bromine. In addition, it is used in the synthesis of urea derivatives that exhibit potent antagonistic activity against the P2X4 (purinergic) receptor.

Dibenz[b,f]azepine-5-carbonyl chloride CAS#33948-22-0